About¶

CellViability is a package designed to support the analysis of cell viability assays from TIFF images containing nuclear staining. It was developed to handle the data volume and processing requirements commonly found in High-Content Screening (HCS) and High-Throughput Screening (HTS) workflows.

Using TIFF images and a configuration file (config.json), the package performs the entire processing and analysis pipeline in an automated, reliable, and reproducible manner.

Issues¶

If you encounter any problems or have feature requests, please use the GitHub Issues page.

Before opening a new issue, please search the existing list to ensure your report has not already been submitted.

Scientific Team¶

The CellViability package was developed by:

• Ana A. S. Iacia [1]
• Jacqueline F. Shimizu [1]
• João V. S. Guerra [1]
• José G. C. Pereira [1]
• Kayllany L. S. Oliveira [1,2]
• Pablo S. Silva [1]
• Rafael E. Marques [1]
• Thayná M. Avelino [1]

Funding¶

This work was supported by the Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) [Grant Number 2025/05515-6], and Brazilian Center for Research in Energy and Materials (CNPEM).

Affiliations¶

[1] Laboratório Nacional de Biociências (LNBio), Centro Nacional de Pesquisa em Energia e Materiais (CNPEM).

[2] Ilum Escola de Ciência, Centro Nacional de Pesquisa em Energia e Materiais (CNPEM).

License¶

This software is licensed under the terms of the GNU General Public License version 3 (GPL3) and is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU General Public License for more details.